If only a SUPERBUG was a cartoon character that defended all the good and defenseless bugs in the world. Sadly, a Super Bug is a pathogenic microorganism that has developed resistance to antibiotic drugs.
A new and novel approach to fighting these superbugs has been developed by a group of researchers from the University of Montreal in Canada.
It’s not a new drug.
Rather, researchers focused their efforts on a chemical molecule that is identified as the pathway to reduce the transfer of antibiotic-resistant genes. These genes were coded onto plasmids (DNA fragments that can carry genes that encode the proteins that render bacteria drug-resistant).
Scientists have found the exact binding sites for these proteins, which are essential in plasma transfer. This discovery allowed them to design more potent chemical molecules to stop the spread of antibiotic-resistant genes.
According to a report by a special commission set up in the United Kingdom in 2014 called the Review on Antimicrobial Resistance, drug-resistant bacteria could take the lives of some 10 million people by 2050. This isn’t particularly difficult to imagine since antibiotic-resistant bacteria infect 2 million people in the U.S. alone every year, according to the Centers for Disease Control and Prevention (CDC), and at least 23,000 of these cases are fatal. Additionally, the WHO reports that there are about 480,000 of multi-drug resistant tuberculosis cases around the world every year.
According to a study published in the journal Scientific Reports earlier this November, the team of researchers is currently working on developing inhibitors to be used in clinical settings to address a global deadly problem.